Anthony,
The answer is both yes and no:
If you have the "old" gas system with bottle mounted regulators and low pressure tubing connecting to, say a Gaslow manual change-over valve, then yes.
If you have the "new" gas system with a single bulkhead mounted regulator, two high pressure pig-tails, and something like a GasLow T piece or change-over, then I'd say no.
In the first example, the worst that could happen from user mismanagement is that the gas going to the van is a blend of low pressure propane and butane at 30 milliBar (0.5 psig) - so it would actually be similar to you using LPG (natural mix of propane and butane)
In the second example, the worst that could happen is that both bottles become interconnected at high pressure - in this case the butane bottle typically has an internal pressure of 4 bar (60 psig) and the propane bottle has a pressure of 14 bar (200 psig) - and this time the propane bottle would potentially over-pressurise the butane bottle.
There are safety features in the T piece connectors and pig-tails to stop this happening, but it's best to avoid this possibility if you have the high pressure system.
Robert