You will need a permanent address for correspondence, tax, insurance and the like, presumably a family member or friend will help.
One major problem is going to be maintenance, what will you do when it needs servicing or if it breaks down and is off the road for any length of time? People do manage it but I am not sure how. Possibly a car and caravan would work better as these things are easier to get round with them.
Do remember though that a motorhome is a depreciating asset and has a finite life no matter how well you look after it and you need a plan to cover this.
Hopefully someone who has tried this can help.