Omicron enhances neutralising immunity against Delta

Nov 11, 2009
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Interesting as Omicron could be a life saver in a round about way and may be the answer to the pandemic? See HERE for for information
That’s an interesting view. I also read that those vaccinated with a Astra Zeneca might be showing better resistance to Omicron than those given Pfizer or Moderna type vaccines. This is thought to be because AZ being based on a more traditional approach “ trains” the bodies immune system to respond in more depth by initiating T cell responses, which could give far longer immunity. But of course it is still early days.
 
Sep 26, 2018
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Hmmm 33 patients? Hardly a statistically valid sample. Agreed it may be worth then conducting more research in a more relevant country (UK vaccination rate >80%, RSA c.25%, Uk population average age 15 years older than RSA)
 
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Hmmm 33 patients? Hardly a statistically valid sample. Agreed it may be worth then conducting more research in a more relevant country (UK vaccination rate >80%, RSA c.25%, Uk population average age 15 years older than RSA)
Strangely the SA scientists are probably streets ahead of any UK, USA etc scientists when it comes to viruses.
Unfortunately when it comes to many population statistics in SA they will be way out as they do not even know the population of SA due to people moving around and never registering for government aid etc.
There could be 50 million people in SA or there could be on 45 million as even a census cannot track down all the population.
 
Nov 11, 2009
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Strangely the SA scientists are probably streets ahead of any UK, USA etc scientists when it comes to viruses.
Unfortunately when it comes to many population statistics in SA they will be way out as they do not even know the population of SA due to people moving around and never registering for government aid etc.
There could be 50 million people in SA or there could be on 45 million as even a census cannot track down all the population.
Our census is probably affected by similar findings too, as if you shouldn’t be here you are not likely to submit a return.
 
Jun 20, 2005
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I am aware the Forum rules may not allow this post but Covid is so relevant to our hobby I hope it is ok. If not I am happy for my comments to be removed.

Interesting paper from SA. Meanwhile back at the ranch

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Prof Ferguson who blotted his copy book last year says otherwise. I know first hand his major role in the Foot and Mouth caused the unnecessary deaths of over a million cattle. The algorithm was subsequently proven flawed. I am not convinced the London paper is valid.
The SA report is based on facts not forecasts so does have some credibility notwithstanding the small numbers involved.
The sooner we can all get a long term high immunity the sooner we can back to caravanning in the real sense
 
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Nov 11, 2009
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But the paper by Imperial College clearly states that it hasn’t been peer reviewed yet, so questioning its proven could be premature and also it wasn’t produced by Professor Ferguson. There’s still a lot of unknowns about how various variants interact with the vaccine types. It’s like squeezing twenty years of research and trials into two years.
 
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But the paper by Imperial College clearly states that it hasn’t been peer reviewed yet, so questioning its proven could be premature and also it wasn’t produced by Professor Ferguson. There’s still a lot of unknowns about how various variants interact with the vaccine types. It’s like squeezing twenty years of research and trials into two years.
The SA one was also “not peer reviewed “ Prof F I thought supported Imperial’s view. I mention him as an example of boffins relying on algorithm projections as opposed to real time findings in SA. That’s all.
 
Jul 18, 2017
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Our daughter in South Africa recovered from Covid although it is unsure which variant however it is suspected it was the Omincron variant. I think their vaccination was Johnson & Johnson the Astra and Pfizer versions seems to affect people there differently for some reason.
 
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The SA one was also “not peer reviewed “ Prof F I thought supported Imperial’s view. I mention him as an example of boffins relying on algorithm projections as opposed to real time findings in SA. That’s all.
Surely all modelling projections rely to some extent or another on algorithms however they be defined. As data is obtained it can be used to refine the algorithm such that it should become more accurate in its predictive outcomes. The SA results are clearly real world but with only 33 collected you would not class it as statistically of high confidence. But it will be very useful to inform further studies.
 
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Surely all modelling projections rely to some extent or another on algorithms however they be defined. As data is obtained it can be used to refine the algorithm such that it should become more accurate in its predictive outcomes. The SA results are clearly real world but with only 33 collected you would not class it as statistically of high confidence. But it will be very useful to inform further studies.

Prof F quoted comments only relate to the public health threat posed by Omnicron. He didn’t seem to endorse or criticise the papers findings.

I would think that they would start with a small selection before expanding. Also remember that a vast majority of the population are still very superstitious and wary which could be why there is such a low take up of the vaccination Rumours revolve round that it could be an evil plot by Western countries to make people sick and take over the country. I kid you not!
 
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A sample of only 33 is far too small on which to base world wide predictions. It needs a much broader trial to make any results statistically significant.

It is of course worthy of further research, but its far too soon to make any fact based statements about its efficacy. And certainly far too soon to ditch the more proven methods. And its entirely wrong to give those who are against the vaccination programme another unfounded reason to make life difficult for others.
 
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A sample of only 33 is far too small on which to base world wide predictions. It needs a much broader trial to make any results statistically significant.

It is of course worthy of further research, but its far too soon to make any fact based statements about its efficacy. And certainly far too soon to ditch the more proven methods. And its entirely wrong to give those who are against the vaccination programme another unfounded reason to make life difficult for others.

Not sure why you think it is wrong as it specifically states; The study, which has not been peer-reviewed, found that people who were infected with Omicron, especially those who were vaccinated, developed enhanced immunity to the Delta variant.

Doesn't that indicate that they will doing further tests due to the results on the small sample of tests already done to establish whether their current conclusion has any merit? I don't think any one mentioned world wide predictions etc. and whether it was fact etc?
 
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Surely all modelling projections rely to some extent or another on algorithms however they be defined. As data is obtained it can be used to refine the algorithm such that it should become more accurate in its predictive outcomes. The SA results are clearly real world but with only 33 collected you would not class it as statistically of high confidence. But it will be very useful to inform further studies.
They are Clive. Exactly. Mathematical predictions. I was trying to move away from that form and take heed from Buckman’s latest . Clearly there is something relevant in the SA findings even though the current numbers are small. Real time rather than algorithms but still a long way to go. A glimmer of hope maybe😉😉
 
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Unfortunately there are still too many people who think the vaccination programme is a government conspiracy, and it consists of tracking systems and other ridiculous conceptions which they use as a reason not to get vaccinated.

They will grab any headline that seeks to negate the need for the vaccines, and the headline on the article you exposed is meat and two veg for them to further avoid getting vaccinated.

I totally agree the article goes on to point out the scale of the study is far too small to be used as the sole basis to adopt the policy, but the groups against vaccinations will only see the headline and conveniently ignore the detail.
 
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We know a couple who think the swab tests contain an agent to destroy your brain-honestly, and that the vaccine gives you covid-so they won't come near anyone who has it-surely logic says if someone wanted rid of us that badly there would be far more effective ways !! I really don't know where they get it from-dark web? Loonacy abounds-I got Vaxxers for Christmas-written by the ladies who developed the Oxford vaccine-they dosed themselves so can't imagine why they would want to self harm-seem wonderful people! I'll have any jab they give me!
 
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Parksy

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Nov 12, 2009
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I know somebody who won't be vaccinated against Covid because 'they don't know what's in it'.
They have no problem with smoking hand rolling tobacco though 🙄
I can't help wondering if, in later life, they would refuse a potentially life saving treatment in hospital if it had only been available for a relatively short time?
The 'it won't happen to me' syndrome among younger people seems to be at work here.
On public social media sites such as Twitter there are comments about being 'pure blood' and 'holding the line' from some of these imbeciles who are, in effect, holding the rest of us to ransom.
 
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I was watching the news and two ladies around 60 ish were interviewed as they attended for their first jab in Lambeth. One had just retired from a senior job at UCL and felt that since UCL were doing so much to fight covid she should do her part. Where has she been for two years? But the other feeling I get is that more people have been moved to action because they fear Omicron. Whether this is due to the publicity given to its speed of transmission or the reduced efficacy of vaccines I don’t know. But if fear motivates people so be it.
 
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I was watching the news and two ladies around 60 ish were interviewed as they attended for their first jab in Lambeth. One had just retired from a senior job at UCL and felt that since UCL were doing so much to fight covid she should do her part. Where has she been for two years? But the other feeling I get is that more people have been moved to action because they fear Omicron. Whether this is due to the publicity given to its speed of transmission or the reduced efficacy of vaccines I don’t know. But if fear motivates people so be it.

I saw the same and thought the same. The other lady was a teacher. I was flabbergasted.

John
 
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We have not seen the end of new mutations, and I do not believe Omicron will be the last variant that poses a high risk to humans in this pandemic.

The original virus that jumped to humans must have come from somewhere, and as far as I know we have not yet fully identified the host species that produced it. What this means the virus will still be present in that species and continuing to mutate. There is every probability another variant will evolve that can jump to humans but will be sufficiently differnt to Covid-19 that our present vaccines and immunities will be less effective against it.

It will happen again.

We need to learn as much as we can about C19, and use it to plan better for future viruses, but as happened with C19, it was new, and we had no textbooks telling us how to deal with it. And that is still true today, each country is taking its own measures to attempt to manage it, and we are seeing divergencies of methods. Even within the UK the devolved governments are taking differnt approaches. Its only after the event that you can actually analyse how effective each strategy has been.

Covid will continue to be a serious virus until it is either eradicated ( which I believe is never going to happen), or the symptoms it produces can be managed with no more trouble than the common cold.
 
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Jun 20, 2005
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This goes some way to explain ” The Origin of the Species” 😉.
https://www.nature.com/articles/d41586-021-00502-4

I agree Prof there will be many more variants, just like the influenza virus. How many letters of the Greek alphabet are left😜
If zoonosis is responsible for transmission and mutation where will that leave us with our pets etc. IMO I don’t think animals will play a large part going forward but who knows.
 
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This goes some way to explain ” The Origin of the Species” 😉.
https://www.nature.com/articles/d41586-021-00502-4

I agree Prof there will be many more variants, just like the influenza virus. How many letters of the Greek alphabet are left😜
If zoonosis is responsible for transmission and mutation where will that leave us with our pets etc. IMO I don’t think animals will play a large part going forward but who knows.
Plant of Apes comes to mind when a disease killed off dogs and cats etc. and people adopted apes to replace them dogs and cats. :D
 
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