If you use sikaflex that part will never come off again in you ever need to remove it.
For a simple side seal like that, a good quality 'tape' mastic is more than sufficient (and is what a dealer would use if they were fitting it)
If you're fitting the square pump connector into the caravan side, carefully mark and drill the corners and use a pad saw to join up the holes and produce the square cutout.
Then rake out the polystyrene insulation to a depth sufficient to allow for pieces of 25mm x 25mm timber to be fitted top, sides, and bottom.
This will give the screws something to bite into when you screw the plastic fitting into place onto its tape mastic bed.
It sounds more complicated than it is - it only takes a few minutes and it's the difference between a good job and a bodge.